CASE OF THE MONTH

Metastatic Adenosquamous Carcinoma



A 66 year old woman presented with abdominal pain.  A CT scan showed a mass in the head of the pancreas as well as multiple liver lesions.  FNA of a liver lesion revealed metastatic carcinoma with both squamous and glandular differentiation.    Immunoperoxidase stains showed that the neoplastic cells were positive for p63 and CK5 and negative for TTF-1, CD15, and Ca19-9.  Mucicarmine stain was positive.  A diagnosis of metastatic adenosquamous carcinoma was made.

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